SARS-CoV-2 spike, closed prefusion
Closed-trimer prefusion conformation of the spike glycoprotein. The starting state for receptor-binding-domain opening dynamics.
SVSofia Vargas
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The spike glycoprotein of coronaviruses is a trimeric class-I fusion protein on the viral surface. It binds host receptors via its receptor-binding domain, then refolds dramatically to drive membrane fusion.
Closed-trimer prefusion conformation of the spike glycoprotein. The starting state for receptor-binding-domain opening dynamics.