CRISPR-Cas9 with sgRNA and DNA
Cas9 bound to a single-guide RNA and target DNA. The complete editing complex in a cleavage-ready geometry.
MAMarcus Adebayo
000
CRISPR-Cas9
Cas9 is the RNA-guided DNA endonuclease at the heart of CRISPR genome editing. Loaded with a single-guide RNA, it scans for complementary DNA and cleaves both strands at a defined site.
1Simulation
2.50 ÅAverage resolution
1Contributor