Protein kinase A, catalytic subunit
PKA catalytic subunit bound to ATP and substrate peptide — the textbook reference structure for protein kinases.
DCDaniel Cohen
000
Protein kinases catalyze the transfer of a phosphate group from ATP onto specific residues of substrate proteins. They are central regulators of nearly every signaling pathway in eukaryotic cells.
PKA catalytic subunit bound to ATP and substrate peptide — the textbook reference structure for protein kinases.
Src tyrosine kinase in its closed, autoinhibited conformation — the regulatory baseline that activation has to overcome.