CRISPR-Cas9 with sgRNA and DNA

Cas9 bound to a single-guide RNA and target DNA. The complete editing complex in a cleavage-ready geometry.

Related simulations

Other simulations in CRISPR-Cas9.

Protein kinase A, catalytic subunit

PKA catalytic subunit bound to ATP and substrate peptide — the textbook reference structure for protein kinases.

EnzymeKinases1ATP

DCDaniel Cohen

000

Src tyrosine kinase, autoinhibited

Src tyrosine kinase in its closed, autoinhibited conformation — the regulatory baseline that activation has to overcome.

EnzymeKinases2SRC

APAnya Petrova

000

Hen egg-white lysozyme

Classic 129-residue enzyme that cleaves bacterial cell walls. A long-standing benchmark for force-field validation and protein dynamics.

EnzymeLysozymes1AKI

MOMira Okafor

000